Zanthoxylum ailanthoides bark, tree, prickly ash species

Also called Japanese Prickly-ash, Zanthoxylum ailanthoides is a tree that grows in Asia. Zanthoxylum ailanthoides Siebold & Zucc. is one of the most frequently encountered pioneer trees in Japanese warm-temperate evergreen oak forests.

Benefit
The resin contained in the bark, and especially in that of the roots, is promoted as a cough suppressant. As of April 2010, human research with this herb could not be found.

Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low density lipoprotein and accumulation of lipid in differentiated THP-1 cells.
Food Chem Toxicol. 2009 Feb 27. Chu CY, Lee HJ, Chu CY, Yin YF, Tseng TH. Institute of Biochemistry and Biotechnology, Chung Shan Medical University, No. 110, Section 1, Chien-Kuo N. Road, Taichung, Taiwan.
It has been reported that extracts of stem and leaf of Zanthoxylum ailanthoides possess antioxidative properties. However, the biological importance of the Zanthoxylum ailanthoides is not well known. In our preliminary study, it showed that Zanthoxylum ailanthoides prepared from 75% alcohol highly contains flavonoids (5.8%) including rutin and hyperoside. Our results demonstrate the protective effect of Zanthoxylum ailanthoides extract on LDL oxidation and lipid accumulation in macrophage.

Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils.
J Nat Prod. 2009 Jan;72(1):107-11. Chen JJ, Chung CY, Hwang TL, Chen JF. Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 907, Taiwan, Republic of China.
Five new compounds, ailanthamide, N-(4-methoxyphenethyl)-N-methylbenzamide, (2E,4E)-N-isobutyl-6-oxohepta-2,4-dienamide, 4-(4'-hydroxy-3'-methylbutoxy)benzaldehyde, and (E)-methyl 4-[4-(3-hydroxypropyl)phenoxy]-2-methylbut-2-enoate, and 17 known compounds have been isolated from the stem bark of Zanthoxylum ailanthoides.

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